Superantigens: Just Like Peptides Only Different

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چکیده

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Superantigens: Just Like Peptides Only Different

T he exotoxins produced by Staphylococcus aureus and Streptococcus pyogenes are prototype molecules for the larger family of superantigens (SAGs). This family now includes many structurally unrelated molecules of disparate origins reflecting a wide evolutionary convergence towards the common goal of subverting T cell antigen recognition. SAGs bind simultaneously to MHC class II molecules and TC...

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Commentary Superantigens : Just Like Peptides Only Different

T he exotoxins produced by Staphylococcus aureus and Streptococcus pyogenes are prototype molecules for the larger family of superantigens (SAGs). This family now includes many structurally unrelated molecules of disparate origins reflecting a wide evolutionary convergence towards the common goal of subverting T cell antigen recognition. SAGs bind simultaneously to MHC class II molecules and TC...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1998

ISSN: 0022-1007,1540-9538

DOI: 10.1084/jem.187.6.819